Hong Chen, Professor
Dean, College of Chemistry, Chemical Engineering and Materials Science
Director, Department of polymer science and engineering
Editor, Colloids and Surface B:Biointerfaces
199 Ren-Ai Road, Suzhou Industrial Park, Suzhou, Jiangsu 215123, P. R. China
Tel: 86-512-65880827; +86-512-65880827
Fax: 86-512-65880583; +86-512-65880089
Education and Working Experience
Hong Chen, a professor at the College of Chemistry, Chemical Engineering and Materials Science at Soochow University, Suzhou, China. Her research interests include: Surface modification and functionalization of biomaterials, Interaction of protein/cell and biomaterials, Hemocompatibility of biomaterials, and Biological detection. Professor Hong Chen earned her Ph.D. degree from Nanjing University, China in 2001 studying polymeric biomaterials. She was a postdoc. at McMaster University, Canada, 2001-2004. After returning back to China, she held a full professor position at Wuhan University of Technology, Wuhan, China from 2004 to 2009. Her research group moved to Soochow University, Suzhou, in 2010. She has been the PI of more than 10 national research projects funded by the Ministry of Science and Technology of China, the Ministry of Education of China and the National Natural Science Foundation of China, including a Major International Joint Research Project. She is the winner of National Science Fund for Distinguished Young Scholars (2011). She was also supported by the program for Talents of Jiangsu Province (2010), the Ministry of Education Program for New Century Excellent Talents in University (2006), the Excellent Youth Foundation of Hubei province (2005). She is an Editorial Board member of Colloids and Surface B and Polymer Chemistry (RSC). She was a guest editor for the special issue: “Biointerfaces in China” published in 2011 and became an editor of Colloids and Surface B since 2013. She has published more than 70 research articles in various peer reviewed journals.
Surface modification and functionalization of biomaterials
Interaction of protein/cell and biomaterials
Hemocompatibility of biomaterials
1. Reductase-like Activity of Silicon Nanowire Arrays. H. Wang, W. Jiang, L. Yuan*, L. Wang, H. Chen*.ACS Appl. Mater. Interfaces, 2013,DOI: 10.1021/am3031322.
2. Poly (N-vinylpyrrolidone)-Modified Surfaces for Biomedical Applications. X. Liu, Y. Xu, Z. Wu*, H. Chen*. Macromol. Biosci.,2013, DOI: 10.1002/mabi.201200269
3. Thermally responsive silicon nanowire arrays for native/denatured-protein separation. H. Wang, Y. Wang, L. Yuan*, L. Wang, W. Yang, Z. Wu, D. Li, H. Chen*. Nanotechnology, 2013, 24, 105101.
4. Vinyl-monomer with lysine side chains for preparing copolymer surfaces with fibrinolytic activity. Z. Tang, D. Li, X. Liu, Z. Wu*, W. Liu, J. L. Brash, H. Chen*.Polym. Chem., 2013, 4, 1583.
5. A new t-PA releasing concept based on protein-protein displacement. D. Li, S. Wang, Z. Wu, H. Chen*, J. L. Brash. Soft Matter, 2013,9, 2321.
6. Block Copolymer Modified Surfaces for Conjugation of Biomacromolecules with Control of Quantity and Activity. X. Li, M. Wang, L. Wang, X. Shi, Y. Xu, B. Song, H. Chen*.Langmuir, 2013,29, 1122.
7. Catalase-like and Peroxidase-like Catalytic Activities of Silicon Nanowire Arrays. H. Wang*, W. Jiang, Y. Wang, X. Liu, J. Yao, L. Yuan, Z. Wu, D. Li, B. Song,H. Chen*.Langmuir, 2013,29, 3.
8. Cell Adhesion on a POEGMA-Modified Topographical Surface. X. Shi, Y. Wang, D. Li, L. Yuan*, F. Zhou, Y. Wang, B. Song, Z. Wu, H. Chen*, J. L. Brash. Langmuir, 2012, 28, 17011.
9. Enhancing Specific Binding of L929 Fibroblasts: Effects of Multi-scale Topography of GRGDY Peptide Modified Surfaces. F. Zhou, D. Li, Z. Wu, B. Song, L. Yuan*,H. Chen*. Macromol. Biosci., 2012,12,1391
10. Inhibitory effect of silicon nanowires on the polymerase chain reaction. H. Wang, L. Wang, L. Yuan*, W. Wang, J. L. Brash, H. Chen*. Nanotechnology, 2012,26, 365101.
11. Sensitive sandwich ELISA based on a gold nanoparticle layer for cancer detection. F. Zhou, M. Wang, L. Yuan*, Z. Cheng, Z. Wu, H. Chen*.Analyst, 2012,137, 1779.(Cover Article)
12. Poly(N-vinylpyrrolidone)-modified poly(dimethylsiloxane) elastomers as anti-biofouling materials. Z. Wu, W. Tong, W. Jiang, X. Liu, Y. Wang, H. Chen*.Colloid Surface. B, 2012,96, 37.
13. Protein-resistant and fibrinolytic polyurethane surfaces. Z. Wu, H. Chen*, X. Liu, J. L. Brash*. Macromol. Biosci., 2012,12, 126.
14. Facile Synthesis of Thermally Stable Poly(N-vinylpyrrolidone)-Modified Gold Surfaces by Surface-Initiated Atom Transfer Radical Polymerization. X. Liu, K. Sun, Z. Wu*, J. Lu, B. Song, W. Tong, X. Shi, H. Chen*. Langmuir, 2012,28, 9451.
15. Cell adhesion on chiral surface: The role of protein adsorption. F. Zhou, L. Yuan*, D. Li, H. Huang, T. Sun, H. Chen*.Colloid Surface. B, 2012,90, 97.
16. Gold Nanoparticle Layer: A Promising Platform for Ultra-Sensitive Cancer Detection. F. Zhou, L. Yuan*, H. Wang, D. Li, H. Chen*.Langmuir, 2011,27, 2155.
23. Predicting Au-S bond breakage from the swelling behavior of surface tethered polyelectrolytes. Y. Zhang, B. E. Lv, Z. Lu, J. A. He, S. Zhang, H. Chen*, H. Ma*. Soft Matter, 2011, 7, 11496.
27. Conformational Changes of Protein Adsorbed on Tailored Flat Substrates with Different Chemistries. H. Huang*, J. Xie, X. Liu, L. Yuan, S. Wang, S. Guo, H. Yu, H. Chen*, Y. Zhang, X. Wu.Chemphyschem, 2011,12, 3642.
29. A surface decorated with diblock copolymer for biomolecular conjugation. Y. Zhang, Q. Yu, H. Huang*, F. Zhou, Z. Wu, L. Yuan, D. Li, H. Chen*.Soft Matter, 2010,6, 2616.
32. pH-Reversible, High-Capacity Binding of Proteins on a Substrate with Nanostructure. Q. Yu, H. Chen*, Y. Zhang, L. Yuan, T. Zhao, X. Li, H. Wang.Langmuir, 2010,26, 17812.
34. Fabrication of cell pattern on poly(dimethylsiloxane) by vacuum ultraviolet lithography. J. Gan, H. Chen*, F. Zhou, H. Huang, J. Zheng, W. Song, L. Yuan, Z. Wu.Colloid Surface. B, 2010,76, 381.
41. Fibrinolytic poly(dimethyl siloxane) surfaces. H. Chen, L. Wang, Y. Zhang, D. Li, W. G. Mcclung, M. A. Brook, H. Sheardown, J. L. Brash.Macromol. Biosci., 2008,8, 863.